Close-up of the EXOSOME repair serum amber dropper bottle. Exosomes are cell-secreted vesicles 30 to 150 nanometres across, carrying repair proteins and RNA; the formula also contains NMN to support recovery after UV exposure
Woman applying EXOSOME repair serum to her cheek with a dropper, beside the amber bottle labelled derived from human adipose stem cells. Exosomes are cell vesicles 30 to 150 nanometres across; the formula also contains NMN

EXosome ES-1 Pure

Regular price $600.00
Unit price per

Exosome Repair Miracle: Rediscover Your Skin's Youthful Radiance!

[One Bottle Solution for Multiple Skin Concerns: Aging, Sensitivity, Roughness, and More!]

Result of years of joint research by the University of Tokyo and Kanazawa Medical University.

Main Ingredients
🌟Exosomes: Promote cell repair and regeneration, enhancing skin elasticity and hydration.
🌟NMN (Nicotinamide Mononucleotide): Anti-aging and antioxidant, improves skin elasticity and radiance, reduces pigmentation.
🌟Propylene Glycol: Deeply locks in moisture for effective hydration.
🌟Natural Trehalose: Soothes and firms skin, enhances smoothness.

Main Benefits
Promotes the secretion of collagen, elastin, and matrix components, stimulating angiogenesis necessary for cell growth.
Suppresses excessive inflammatory responses.
Inhibits scar formation.
Lightens spots, brightens, lifts and firms, repairs.

Suggested Use: Apply 2-3 drops evenly to cleansed skin. Can be used with beauty devices.

Suitable for: All skin types, including sensitive skin.

Volume: 5ml

Shelf Life: 3 years (3-6 months after opening)

Product Overview

[The Exosome Repair Miracle: Rediscover Your Skin's Youthful Radiance!]
[One Bottle Solution for Multiple Skin Concerns: Aging, Sensitivity, Roughness, and More!]

EXosome ES-1 Pure is packed with rich repair ingredients like exosomes and collagen, effectively promoting cell regeneration, firming and repairing skin, soothing inflammation, fading dark spots, and enhancing skin elasticity and hydration. Suitable for all skin types, even sensitive skin. Using advanced human stem cell extraction technology and exosome cultivation methods, it meets the suitability consultation qualifications for regenerative medicine product materials, restoring youthful and healthy skin.

Main Ingredient Benefits:
🌟 Exosomes: Promote cell repair and regeneration, enhancing skin elasticity and hydration.
🌟 NMN (Nicotinamide Mononucleotide): Anti-aging and antioxidant, improves skin elasticity and radiance, reduces pigmentation.
🌟 Propylene Glycol: Deeply locks in moisture for effective hydration.
🌟 Natural Trehalose: Soothes and firms skin, enhances smoothness.
Detailed Introduction:

The result of years of joint research by the University of Tokyo and Kanazawa Medical University, using advanced human stem cell extraction technology and exosome cultivation methods. Cell culture is carried out under strict Class 1000 and Class 10000 management. Meets suitability consultation qualifications for regenerative medicine product materials.

Main Benefits:
✅ Promotes collagen, elastin, and matrix component secretion.
✅ Stimulates angiogenesis necessary for cell growth.
✅ Suppresses excessive inflammatory responses.
✅ Inhibits scar formation.
✅ Lightens spots, brightens, lifts, firms, and repairs.

Main Ingredients

What are Exosomes?
Exosomes are tiny vesicles secreted by cells, a true "skin repair miracle." These particles, only 30-150 nanometers in diameter, are packed with substances necessary for cell repair and regeneration, such as proteins and RNA.

Exosomes are absorbed by other cells and delivered precisely to areas needing repair, firming and brightening skin while providing powerful antioxidant effects that effectively slow down skin aging.

Whether your skin is facing roughness, sensitivity, dark spots, or loss of elasticity, exosomes can help. Simply apply an exosome-rich essence to your face, and these tiny "repair specialists" will work silently within your skin to restore your youthful complexion. Ladies, exosomes are your best allies for healthy, smooth skin!

The exosome extraction method combines 20 years of research with cutting-edge Japanese technology. 🇯🇵 Through multiple rounds of centrifugation at varying degrees, exosome supernatant is separated from the culture supernatant to obtain higher purity exosomes. The amount of exosomes extracted each time is minimal, making them extremely rare.

Other Ingredients:
NMN (Nicotinamide Mononucleotide): A derivative of Vitamin B3 (niacin), research shows NMN can slow down cell aging and improve skin condition. NMN converts to NAD+, essential for boosting metabolism and restoring youthful bodily functions. Long-term NMN use can eliminate harmful free radicals, improve skin elasticity, reduce fine lines, and restore a youthful, vibrant appearance. Daily UV exposure reduces NAD+ in the skin, accelerating aging and causing uneven skin tone. The NMN in EXosome ES-1 Pure Exosome Essence can restore the skin's ability to recover from UV damage, effectively combating aging.

Propylene Glycol: A plant-derived humectant that increases moisture in the stratum corneum. It also has antibacterial properties, helping to repair and maintain skin health. Its effects are equivalent to DPG (Dipropylene Glycol) and 1,3-Propanediol.
Natural Trehalose: Forms a protective film on the skin's surface, preventing aging and keeping skin plump and supple. It soothes, firms, moisturizes, and enhances skin smoothness. It also protects skin cells from UV damage and inhibits dryness and inflammation.
Product Information:

Brand: Japan Healthcare Institute Inc.
Name: EXosome ES-1 Pure
Volume: 5ml
Shelf Life: 3 years (3-6 months after opening)
Country of Origin: Japan
Benefits: Effectively provides collagen, promotes cell growth, soothes inflammation, repairs acne scars, lightens spots, brightens, firms, and repairs.
Suitable for: All skin types, including sensitive skin.

How to Use

How to Use
Apply 2-3 drops evenly to cleansed skin. Can be used with beauty devices.

Frequently Asked Questions

How many drops, and how do I apply it?

After cleansing, prepare skin with toner, then apply 2 to 3 drops evenly to clean skin and pat in. Follow with your usual moisturiser. Can be used alongside a beauty device to enhance delivery.

What exactly are exosomes?

Exosomes are microscopic vesicles secreted by cells, only 30–150 nanometres across, carrying the proteins and RNA cells need for repair and renewal. Other cells absorb them and deliver that cargo precisely where repair is needed — targeted delivery rather than broad application.

Is it suitable for sensitive skin? What about after treatments?

Suitable for all skin types, including sensitive skin. It also suits post-treatment recovery, as the formula helps calm excessive inflammatory response and inhibit scar formation.

How long does it keep after opening?

Three years unopened; use within 3 to 6 months of opening. 5ml, made in Japan.

What does the NMN in it do?

NMN is a vitamin B3 derivative that converts to NAD+ to support metabolism. Everyday UV exposure depletes NAD+ in the skin and accelerates ageing; NMN helps restore recovery capacity after UV damage. That makes this serum particularly suited to people who are often outdoors.